Including previously reported cases, there are now at least 19 U.S. deaths associated with poppy seeds in the literature. For centuries there has been cultivation of cannabis, coca, and the opium poppy. From the opium poppy has come morphine drips in hospitals, from the coca plant has come cocaine which is used in certain medical surgeries, and from the cannabis plant has come various hemp products. While these plants have provided useful products, they are also among nature’s most addicting and potentially deadly vegetation. This exhibit provides an overview of these “Big Three” addictive plants. Can poppy seeds cause a positive anti-doping drug test? How does eating poppy seeds cause a failed drug test. Can you test positive after eating poppy seeds?
Opioid exposure associated with poppy consumption reported to poison control centers and the U.S. Food and Drug Administration
Including previously reported cases, there are now at least 19 U.S. deaths associated with poppy seeds in the literature. Authors recommend that practitioners working in opioid treatment and recovery be alert to use of poppy to treat pain and symptoms of withdrawal.
- Eva Greenthal , Peter Lurie & Suzanne Doyon (2021): Opioid exposure associated with poppy consumption reported to poison control centers and the U.S. Food and Drug Administration, Clinical Toxicology, DOI: 10.1080/15563650.2020.1866766
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September 20, 2021 | CDC Alert on the Increased availability of cannabis products containing delta-8 tetrahydrocannabinol (THC) and the potential for adverse events
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FDA Special Announcement: Reports of Seizures After Using Nicotine Vaping Devices
April 4, 2019 | The FDA has become aware that some people who use e-cigarettes have experienced seizures, with most reports involving youth or young adult users.
Cannabis, Coca, and Poppy: Nature’s Addictive Plants
For centuries there has been cultivation of cannabis, coca, and the opium poppy. From the opium poppy has come morphine drips in hospitals, from the coca plant has come cocaine which is used in certain medical surgeries, and from the cannabis plant has come various hemp products. While these plants have provided useful products, they are also among nature’s most addicting and potentially deadly vegetation. This exhibit provides an overview of these “Big Three” addictive plants.
Nature is rich in diversity. There are many different botanicals that have many different uses. Mankind has long sought to harness plants for a variety of purposes. Scientists have conducted research to discover new medicines and cures from plants across the globe.
There is a constant search for medicines that will improve the quality of life, manage or alleviate pain, and cure diseases. Botanicals are one source for those medicines. They can also be sources for other products and chemicals. Some plants have many serious side effects. With cannabis, coca, and the opium poppy, the challenge is a balance between using the products from the plant for their intended use in a safe manner while avoiding the illegal use and misuse that has had so many detrimental effects on society over the centuries.
Poppy Seed Marijuana
While poppy seeds don’t actually contain morphine, the seeds can become coated by, or absorb, opium extract during harvesting. Opium is the milky substance that is extracted along with the poppy seeds from the seed pod of the opium poppy after all the petals have fallen off.
The opium is composed of roughly 12 percent morphine, which is a narcotic that is prohibited in-competition. According to the World Anti-Doping Agency (WADA) Prohibited List, morphine is a threshold substance, meaning that WADA-accredited laboratories determine if a sample is positive for morphine when the level of morphine in the urine is greater than *1.3 micrograms/mL.
Can the morphine from poppy seeds be detected in a sample?
Research shows that morphine and codeine can sometimes be detected in the urine up to 48 hours after ingestion of poppy seeds from some pastries, such as bagels, muffins, and cakes (see reference one for a free article on this topic).
Even though most of the opium is removed from the poppy seeds during processing (usually more than 90%), in some cases, the seeds sold for use in foods still have a significant amount of opium – and thus morphine – on them. The amount of morphine residue left on the seeds depends on how well the poppy seeds are cleaned and processed, which varies depending on the country the seeds are from and how and when they were harvested.
Can athletes eat poppy seeds without testing positive?
USADA cannot predict the amount of poppy seeds you can eat and remain below the testing threshold set by WADA. **In most cases, consumption of poppy seeds in foods will not cause a positive doping test.
However, it may be possible to exceed the morphine threshold by eating foods with poppy seeds and USADA can’t predict how long morphine or morphine metabolites from poppy seeds will stay in your system. The most conservative approach would be to avoid poppy seeds a few days before and during competitions.
Thevis M, Opfermann G, Schänzer W. Urinary Concentrations of Morphine and Codeine After Consumption of Poppy Seeds. J Anal Toxicol (January-February 2003) 27(1): 53-56 . URL: http://www.ncbi.nlm.nih.gov/pubmed?term=morphine%20and%20codeine%20on%20poppy%20seeds%20thevis
Lachenmeier DW, Sproll C, Musshoff F. Poppy seed foods and opiate drug testing—where are we today? Ther Drug Monitor. 2010 Feb; 32(1): 11-18.
Moeller MR, Hammer K, Engel O. Poppy seed consumption and toxicological analysis of blood and urine samples. Forensic Sci Int. 2004 Jun 16; 143(2-3): 183-186.